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KMID : 0364019960290080836
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Korean Journal of Thoracic and Cardiovascular Surgery
1996 Volume.29 No. 8 p.836 ~ p.843
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Changes in the Luminal Surface of the PTFE Graft Used in Systemic Pulmonary Shunt Operation
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Abstract
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Histologic, and scanning electron microscopic observations were made of 12 biopsy specimens from polytetrafluoroethylene (PTFE) grafts that had been implanted as systemic-pulmonary shunt for improving oxygenation of cyanotic congenital heart
disease and
harvested near the end of pulmonary artery side at the time of redo shunt or total correction between 1985 and 1992. The types of shunt operation are modified Blalock-Taussig shunt in 10 cases, Waterston-Cooley shunt in l and Potts shunt in I
case.
The
5mm PTFE graft was used in 10, 4mm in I and 6mm in I case. The mean duration of implantation was 0±14.1 months(from 12 months to 55 months). The platelets were aggregated between gaps of Goretex surface and intimal thickening was noted about 10
to
20
months after implantation. Endothelial cells were found in the 40-months patent PTFE graft6 by light and scanning electron microscopy. In the specimen of poor flow or zero flow graft, severe intimal hyperplasia and thrombi which was made of
platelets
were noted.
Based on this experience, we think that the patency will be maintained well if the connective tissue could be fixed firmly over the inner layer of the Goretes and the endothelial cell layer should form over the connective tissue and plaelet
aggregation
should be prevented.
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